# Magnesium helps Depression and Anxiety Some researchers believe low Magnesium is the problem behind treatment-resistant [[💡 Depression]], because [[Stress and Anxiety deplete Magnesium levels]] and we have [[NMDA Receptor|NMDA receptors]] in our [[💡 Amygdala]], which control [[💡 Fear]] and [[🛡️ Avoiding]] behaviors. [[💡 Magnesium]] is an [[💡 NMDA Receptor Antagonist]], which will [[💡 Amygdala#Decrease Amygdala Activity|Decrease Amygdala Activity]] and our fear response and avoidance. [[Magnesium decreases Glutamate]] [[Magnesium increases GABA]]